San Francisco 49ers vs Carolina Panthers: Prediction, Head-to-Head, Odds & Stats (Tue, 25 Nov '25)
Wojtek Kolan
Published on 18 Nov, 09:53 AM UTC
Next Match 25/11/25 at 01:15 AM
Scheduled H2H Match For San Francisco 49ers Vs Carolina Panthers
NFL
Tue, 25 Nov 2025 at 01:15 AM UTC
USA
Recent Form
4
Win
Last 10 Played
6
Win
USA
Recent Form
4
Win
Last 10 Played
6
Win
Game Schedule - Time Of Fixture
San Francisco 49ers will square off vs Carolina Panthers in NFL on Tue, 25 Nov 2025 at 01:15 AM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.
San Francisco 49ers vs Carolina Panthers H2H Results Summary
In the last 10 H2H results for these teams, San Francisco 49ers have come out on top 4 times and Carolina Panthers have won on 6 occasion. In the last fixture between them, San Francisco 49ers won 15-37.
| Head-to-Head (Last 10 Matches) | |
|---|---|
| San Francisco 49ers | 4 |
| Carolina Panthers | 6 |
San Francisco 49ers Vs Carolina Panthers Performance stats
Editorial Prediction:
San Francisco 49ers are set to go head to head with Carolina Panthers in an NFL matchup on Tuesday, November 25, 2025. In the last ten encounters between the two teams, the San Francisco 49ers have secured victories in four games, while the Carolina Panthers have also triumphed four times.
Looking at their most recent clash on October 9, 2022, the San Francisco 49ers emerged victorious with a 37-15 win as the away team against the Carolina Panthers. Despite this decisive result, the statistical performance comparison for that specific match shows that neither team managed to achieve maximum points in any streak, and both teams had the same number of comebacks, which remained at zero. Additionally, both teams failed to convert any receiving opportunities into points.
Heading into this upcoming game, the San Francisco 49ers come with momentum from a resounding 41-22 victory over the Arizona Cardinals. Similarly, the Carolina Panthers carry some confidence from their recent 30-27 win against the Atlanta Falcons. Based on the comparative performance and recent form, the San Francisco 49ers appear to have a slight edge and are predicted to secure a win in this encounter.
Matchstat.com San Francisco 49ers vs Carolina Panthers Prediction For This Upcoming H2H Match
San Francisco 49ers vs Carolina Panthers Past H2H Matches
09/10/22
27/10/19
10/09/17
18/09/16
12/01/14
10/11/13
24/10/10
02/12/07
14/11/04
18/11/01
08/10/01
San Francisco 49ers Recent Matches
16/11/25
09/11/25
02/11/25
26/10/25
20/10/25
12/10/25
03/10/25
28/09/25
21/09/25
14/09/25
07/09/25
05/01/25
31/12/24
22/12/24
13/12/24
08/12/24
02/12/24
24/11/24
17/11/24
10/11/24
28/10/24
20/10/24
11/10/24
06/10/24
29/09/24
22/09/24
15/09/24
24/08/25
16/08/25
10/08/25
Carolina Panthers Recent Matches
16/11/25
09/11/25
02/11/25
26/10/25
19/10/25
12/10/25
05/10/25
28/09/25
21/09/25
14/09/25
07/09/25
05/01/25
29/12/24
22/12/24
15/12/24
08/12/24
01/12/24
24/11/24
10/11/24
03/11/24
27/10/24
20/10/24
13/10/24
06/10/24
29/09/24
22/09/24
15/09/24
21/08/25
16/08/25
08/08/25
San Francisco 49ers Next Fixtures
25/11/25
30/11/25
14/12/25
23/12/25
29/12/25
04/01/26
Carolina Panthers Next Fixtures
25/11/25
30/11/25
14/12/25
21/12/25
28/12/25
04/01/26
San Francisco 49ers Last Match Played stats
Arizona Cardinals vs San Francisco 49ers
Final Score :22 - 41
| (H) | Offense | (A) |
|---|---|---|
| 3 | Touchdowns | 5 |
| 1/2 | Field goals | 3/3 |
| 488 | Total yards | 281 |
| 3 | Turnovers | 0 |
| 3/5 | Red zone efficiency | 4/5 |
| 34:15 | Time of Possession | 25:45 |
| 24 | First downs | 24 |
| 3 | First downs by penalty | 1 |
| 6/14 (42%) | Third down efficiency | 3/9 (33%) |
| 3 | Punts | 3 |
| 40.7 | Average yards per punt | 46.3 |
| 6.9 | Average yards per play | 5.4 |
| (H) | Passing | (A) |
| 18 | First downs by passing | 13 |
| 452 | Net yards passing | 186 |
| 452 | Gross yards passing | 200 |
| 2 | Passing touchdowns | 3 |
| 2 | Interceptions thrown | 0 |
| 7.9 | Average passing yards per attempt | 6.9 |
| 10 | Red zone passing attempts | 6 |
| (H) | Rushing | (A) |
| 14 | Rushing attempts | 25 |
| 36 | Rushing yards | 95 |
| 2.6 | Average rushing yards per attempt | 3.8 |
| 5 | First downs by rushing | 8 |
| 4 | Red zone rushing attempts | 4 |
| (H) | Other | (A) |
| 17 | Penalties | 1 |
| 130 | Yards penalized | 15 |
| 1 | Fumbles | 0 |
| 1 | Fumbles lost | 0 |
Carolina Panthers Last Match Played stats
Atlanta Falcons vs Carolina Panthers
Final Score :27 - 30
| (H) | Offense | (A) |
|---|---|---|
| 3 | Touchdowns | 3 |
| 2/2 | Field goals | 3/3 |
| 348 | Total yards | 486 |
| 1 | Turnovers | 0 |
| 3/3 | Red zone efficiency | 2/6 |
| 27:43 | Time of Possession | 37:07 |
| 23 | First downs | 22 |
| 0 | First downs by penalty | 4 |
| 4/11 (36%) | Third down efficiency | 6/17 (35%) |
| 5 | Punts | 3 |
| 51 | Average yards per punt | 46.7 |
| 6 | Average yards per play | 6.5 |
| (H) | Passing | (A) |
| 11 | First downs by passing | 20 |
| 223 | Net yards passing | 419 |
| 223 | Gross yards passing | 448 |
| 0 | Passing touchdowns | 3 |
| 0 | Interceptions thrown | 0 |
| 7.4 | Average passing yards per attempt | 8.4 |
| 1 | Red zone passing attempts | 9 |
| (H) | Rushing | (A) |
| 28 | Rushing attempts | 25 |
| 125 | Rushing yards | 67 |
| 4.5 | Average rushing yards per attempt | 2.7 |
| 8 | First downs by rushing | 2 |
| 4 | Red zone rushing attempts | 8 |
| (H) | Other | (A) |
| 6 | Penalties | 8 |
| 44 | Yards penalized | 49 |
| 3 | Fumbles | 0 |
| 1 | Fumbles lost | 0 |
NFL 25/26 Standings
| POS | TEAM | MP | W | L | D | PTS |
|---|---|---|---|---|---|---|
| 1 | Denver Broncos | 11 | 9 | 2 | 0 | 0.818 |
| 2 | New England Patriots | 11 | 9 | 2 | 0 | 0.818 |
| 3 | Philadelphia Eagles | 10 | 8 | 2 | 0 | 0.8 |
| 4 | Los Angeles Rams | 10 | 8 | 2 | 0 | 0.8 |
| 5 | Indianapolis Colts | 10 | 8 | 2 | 0 | 0.8 |
| 6 | Buffalo Bills | 10 | 7 | 3 | 0 | 0.7 |
| 7 | Seattle Seahawks | 10 | 7 | 3 | 0 | 0.7 |
| 8 | Chicago Bears | 10 | 7 | 3 | 0 | 0.7 |
| 9 | Green Bay Packers | 10 | 6 | 3 | 1 | 0.65 |
| 10 | San Francisco 49ers | 11 | 7 | 4 | 0 | 0.636 |
| 11 | Los Angeles Chargers | 11 | 7 | 4 | 0 | 0.636 |
| 12 | Jacksonville Jaguars | 10 | 6 | 4 | 0 | 0.6 |
| 13 | Pittsburgh Steelers | 10 | 6 | 4 | 0 | 0.6 |
| 14 | Detroit Lions | 10 | 6 | 4 | 0 | 0.6 |
| 15 | Tampa Bay Buccaneers | 10 | 6 | 4 | 0 | 0.6 |
| 16 | Carolina Panthers | 11 | 6 | 5 | 0 | 0.545 |
| 17 | Houston Texans | 10 | 5 | 5 | 0 | 0.5 |
| 18 | Baltimore Ravens | 10 | 5 | 5 | 0 | 0.5 |
| 19 | Kansas City Chiefs | 10 | 5 | 5 | 0 | 0.5 |
| 20 | Dallas Cowboys | 10 | 4 | 5 | 1 | 0.45 |
| 21 | Minnesota Vikings | 10 | 4 | 6 | 0 | 0.4 |
| 22 | Miami Dolphins | 11 | 4 | 7 | 0 | 0.364 |
| 23 | Cincinnati Bengals | 10 | 3 | 7 | 0 | 0.3 |
| 24 | Atlanta Falcons | 10 | 3 | 7 | 0 | 0.3 |
| 25 | Arizona Cardinals | 10 | 3 | 7 | 0 | 0.3 |
| 26 | Washington Commanders | 11 | 3 | 8 | 0 | 0.273 |
| 27 | Cleveland Browns | 10 | 2 | 8 | 0 | 0.2 |
| 28 | Las Vegas Raiders | 10 | 2 | 8 | 0 | 0.2 |
| 29 | New Orleans Saints | 10 | 2 | 8 | 0 | 0.2 |
| 30 | New York Jets | 10 | 2 | 8 | 0 | 0.2 |
| 31 | New York Giants | 11 | 2 | 9 | 0 | 0.182 |
| 32 | Tennessee Titans | 10 | 1 | 9 | 0 | 0.1 |