Prediction Of Cobolli Vs Rune H2H, Who Will Win At ATP Mutua Madrid Open 2025?

What Time Will Flavio Cobolli Play Against Holger Rune?

Cobolli and Rune are on the Day 3 Schedule at Mutua Madrid Open 2025 on Friday 25 April 2025. Lets breakdown the career, past stats and recent form of these players and predict who will get the victory.

Who Will Win In This Head-To-Head?

In their previous encounter at the 2024 Roland Garros, Holger Rune from Denmark defeated Flavio Cobolli from Italy in a five-set match. Rune currently leads the head-to-head 1-0.

Flavio Cobolli, aged 22, is currently ranked World No. 36 with a career-high ranking of No. 30. He had a successful year in 2025, with a Bucharest title and a 3-1 record in Madrid in 2024. Cobolli made his breakthrough into the top 200 in January 2022 and the top 100 in October 2023. His career reached its peak in September 2024 when he achieved his career-high ranking soon after his first ATP Tour final appearance in Washington. Cobolli’s victory in the 2025 Bucharest earned him his first ATP Tour title, where he defeated clay court champions Gasquet and Baez. It was a remarkable achievement considering he entered the event on an eight-match losing streak. Additionally, Cobolli’s significant wins include defeating Americans Shelton (No. 15) in the 2024 Geneva tournament to reach his first ATP Tour semifinal, defeating Shelton again and Paul (No. 13) in the 2024 Washington tournament, and defeating No. 18 Jarry in the first round of the Australian Open in 2024. Cobolli has also had a memorable ATP Tour main draw debut, saving three match points against Giron to secure a win. As for his junior career, Cobolli peaked at No. 8 and won the 2020 Roland Garros boys’ doubles title with Stricker. Cobolli, who has a 0-9 record against top 10 players, is striving for the biggest win of his career and his 50th tour-level victory. He aims to reach the third round of an ATP Masters 1000 event for the fourth time after previously achieving this feat in Madrid, Cincinnati, and Shanghai last year.

Holger Rune, aged 21, currently holds the ninth position in the ATP rankings with a career-high ranking of No. 4. He has had an impressive year so far in 2025, with a Barcelona title and a 2-2 record in Madrid in 2023 and 2024. Rune’s rise in the professional circuit began in the juniors, where he became the former World No. 1 junior. He broke into the top 100 in January 2022, the top 50 in May 2022, and the top 10 in November 2022. Rune made history as the highest-ranked Dane in PIF ATP Rankings history (since 1973) when he reached a career-best ranking of No. 4 in August 2023. A remarkable achievement in his career was winning the 2022 ATP Masters 1000 Paris title at the age of 19. Rune became the first player since the start of the ATP Tour in 1990 to secure five top-10 wins at an event other than the Nitto ATP Finals. From the 2022 Paris tournament to the 2023 Rome tournament, Rune had an impressive record of 18-5 in six ATP Masters 1000 events, including runner-up finishes in Monte-Carlo and Rome. He had a marvelous start to his career against top 5 opponents with a 7-match winning streak, which included victories over No. 1 ranked players Alcaraz in the 2022 ATP Masters 1000 Paris and Djokovic in the 2023 ATP Masters 1000 Rome. Rune had a strong finish to the 2022 season with a 19-2 run, although he experienced a slow start with a 1-6 record in January-February and a 0-7 record in June-July. Rune made history at the 2022 Roland Garros by becoming the first Danish man to reach the quarterfinals in the tournament’s history (since 1925) and the first Danish man to reach any Grand Slam quarterfinal in the Open Era (since 1968). In his last five matches, Rune is on a winning streak after winning the Barcelona title, which included a victory over No. 2 ranked Alcaraz in the final. He has a 17-4 record against Italians at the tour-level, which includes a 2-3 record against Sinner and a 4-1 record against Berrettini. Rune is aiming to secure his first ATP Masters 1000 win since reaching the Indian Wells final after early round losses in Miami and Monte-Carlo.

The match between Cobolli and Rune will take place on Stadium 3.

My Conclusion / Prediction:

My pick is that Cobolli will win.
Matchstat.com has an Artificial Intelligence (Ai) prediction model that is trained on all professional ATP and WTA past matches.

To find out who our model thinks will win for Flavio Cobolli vs Holger Rune, have a look at the prediction here:

Matchstat.com Flavio Cobolli vs Holger Rune prediction.