Stefanos Tsitsipas and Lorenzo Musetti Prediction Head To Head Summary

Tsitsipas vs Musetti Prediction:
Derived from odds to give us the implied probability from the moneyline, Musetti has a 67.11% chance to win this match.
Tsitsipas → 2.73. Musetti → 1.49.
BE AWARE: To reveal edge and value bets for this match, check out the Matchstat.com expert prediction pick by clicking here.
Tsitsipas vs Musetti Upcoming Match Details:
Tsitsipas will play Musetti on I.hard court in the First round at the ATP Erste Bank Open event in Vienna Men’s Singles 2025 on 21st October 2025.
Head-to-Head: Tsitsipas 5-2 Musetti
The current Head to Head score is 5-2. Tsitsipas comes into this match with a ranking of 25 , while Musetti is ranked 8.
Tsitsipas vs Musetti Prediction, Tips & Picks Analysis:
- Second serve performance analysis: In matches leading up to this game, Musetti has won 46% of points on his second serve, while Tsitsipas has won 46% and in historical match simulations this is a very important variable in analyzing the outcome.
- Returning game stats analysis: Leading up to this h2h matchup Musetti has won 24% of his opponent’s first serve points, while Tsitsipas has won 24%. The same stats for second serve return points are 43% and 47% respectively which historical data suggests is very important when picking h2h betting tips.
- Performance under pressure prediction: Musetti has been saving 52% of his breakpoints, and Tsitsipas has saved 58% which is a useful statistic for in-game betting predictions.
- Surface prediction: Musetti performs best on Clay, winning 67% (W/L 141/71) and worse career win % on I.hard, winning 46% (W/L 34/40). Tsitsipas performs best on Clay, winning 75% (W/L 202/66), and performs worse on Grass, winning 56% (W/L 27/21).
- In play break point conversion prediction: Lorenzo Musetti has converted 26% of breakpoint opportunities in their recent games and Stefanos Tsitsipas has converted 28% of their chances to get the break which is an important stat in our betting tips system to pick the outcome.
- Last match played: In the match before this one, Stefanos Tsitsipas played Joao Fonseca in the Rubber 4 round at the Davis Cup, Group I, 1R, GRE-BRA 1-3 and lost 6-4 3-6 7-5 . Lorenzo Musetti played Giovanni Mpetshi Perricard in the Quarterfinals at the European Open – Brussels and lost 6-4 7-6(8) in 01:23:43.
Head To Head Performance Stats Vs All Opponents
Unlimited match filtering is available on the detailed stats head to head page where you can also see current event performance stats.

See below for our machine learning AI prediction for Tsitsipas Vs Musetti

Career Performance Prediction Factors In Our Pick:
Tsitsipas has won 22 titles in his career, while Lorenzo Musetti has won 6 events. Tsitsipas has won 52% (59688 of 114548) of points played in his entire career, and Musetti has achieved 51% (33611 of 65823). A great statistic to predict performance under pressure is that, Tsitsipas has won 59% of tie breaks in his entire career (239 of 406), whereas Lorenzo Musetti has won 56% (98 of 176). As per the image above, our algorithm is predicting Lorenzo Musetti has an 73.96% probability of winning this match.
Stefanos Tsitsipas vs Lorenzo Musetti Odds & Betting Tips
Our Prediction: Lorenzo Musetti To Get The Win
After analyzing hundreds of performance variables against all other players in their careers and recent form, as well as head to head performance stats, our pick indicates Stefanos Tsitsipas has a 26.04% chance of winning and Lorenzo Musetti has a 73.96% chance of taking the victory. We tip Musetti to get the win. Whether you should place a bet on this pick or not depends on the likely probability of the player winning relative to the odds
To see all live tennis scores for the Erste Bank Open – Vienna.
