Reilly Opelka and Francisco Comesana Prediction Head To Head Summary

Opelka vs Comesana Prediction:
Derived from odds to give us the implied probability from the moneyline, Opelka has a 62.89% chance to win this match.
Opelka → 1.59. Comesana → 2.44.
BE AWARE: To reveal edge and value bets for this match, check out the Matchstat.com expert prediction pick by clicking here.
Opelka vs Comesana Upcoming Match Details:
Opelka will play Comesana on Hard court in the Third round at the ATP Cincinnati Open event in Cincinnati Men’s Singles 2025 on 12th August 2025.
Head-to-Head: Opelka 0-0 Comesana
The current Head to Head score is 0-0. Opelka comes into this match with a ranking of 73 , while Comesana is ranked 71.
Opelka vs Comesana Prediction, Tips & Picks Analysis:
- Second serve performance analysis: In matches leading up to this game, Comesana has won 48% of points on his second serve, while Opelka has won 49% and in historical match simulations this is a very important variable in analyzing the outcome.
- Returning game stats analysis: Leading up to this h2h matchup Comesana has won 26% of his opponent’s first serve points, while Opelka has won 18%. The same stats for second serve return points are 46% and 40% respectively which historical data suggests is very important when picking h2h betting tips.
- Performance under pressure prediction: Comesana has been saving 58% of his breakpoints, and Opelka has saved 65% which is a useful statistic for in-game betting predictions.
- Surface prediction: Comesana performs best on Clay, winning 65% (W/L 264/141) and worse career win % on I.hard, winning 0% (W/L 0/1). Opelka performs best on I.hard, winning 67% (W/L 46/23), and performs worse on Grass, winning 46% (W/L 17/20).
- In play break point conversion prediction: Francisco Comesana has converted 27% of breakpoint opportunities in their recent games and Reilly Opelka has converted 20% of their chances to get the break which is an important stat in our betting tips system to pick the outcome.
- Last match played: In the match before this one, Reilly Opelka played Alex De Minaur in the Second round at the Cincinnati Open – Cincinnati and won 7-6(6) 6-4 in 01:39:41 . Francisco Comesana played Luciano Darderi in the Second round at the Cincinnati Open – Cincinnati and won 6-4 3-1 ret. in 00:52:56.
Head To Head Performance Stats Vs All Opponents
Unlimited match filtering is available on the detailed stats head to head page where you can also see current event performance stats.

Prediction Stats H2H Summary Of Reilly Opelka and Francisco Comesana
Of their last 10 matches played, Opelka has won 6, while Comesana has won 6. The Matchstat.com prediction algorithm uses about 190 variables. One very important stat for this match is on Hard in recent matches, Opelka has won 52% of his own 2nd serve points and 28% of return points, versus an average opponent rank of 70.2 , while Comesana has won 52% of his own 2nd serve points and 36% of return points, against an average opponent rank of 236.46.
Gemma@MatchStat
See below for our machine learning AI prediction for Opelka Vs Comesana

Career Performance Prediction Factors In Our Pick:
Opelka has won 8 titles in his career, while Francisco Comesana has won 10 events. Opelka has won 50% (30024 of 60074) of points played in his entire career, and Comesana has achieved 52% (27712 of 53721). A great statistic to predict performance under pressure is that, Opelka has won 54% of tie breaks in his entire career (191 of 353), whereas Francisco Comesana has won 52% (66 of 127). As per the image above, our algorithm is predicting Reilly Opelka has an 57.58% probability of winning this match.
Reilly Opelka vs Francisco Comesana Odds & Betting Tips
Our Prediction: Reilly Opelka To Get The Win
After analyzing hundreds of performance variables against all other players in their careers and recent form, as well as head to head performance stats, our pick indicates Reilly Opelka has a 57.58% chance of winning and Francisco Comesana has a 42.42% chance of taking the victory. We tip Opelka to get the win. Whether you should place a bet on this pick or not depends on the likely probability of the player winning relative to the odds
To see all live tennis scores for the Cincinnati Open – Cincinnati, go here.
Potential H2H Matches This Week For Reilly Opelka
- Opelka vs Alcaraz H2H () , could play in The Semifinals
- Opelka vs Medjedovic H2H () , could play in The Semifinals
- Opelka vs Nardi H2H () , could play in The Semifinals
- Opelka vs Mensik H2H () , could play in The Semifinals
- Opelka vs Rublev H2H () , could play in The Quarterfinals
- Opelka vs Popyrin H2H () , could play in The Quarterfinals
Potential H2H Matches This Week For Francisco Comesana
- Comesana vs Alcaraz H2H (undefined), could play in The Semifinals
- Comesana vs Medjedovic H2H (undefined), could play in The Semifinals
- Comesana vs Nardi H2H (undefined), could play in The Semifinals
- Comesana vs Mensik H2H (undefined), could play in The Semifinals
- Comesana vs Rublev H2H (undefined), could play in The Quarterfinals
- Comesana vs Popyrin H2H (undefined), could play in The Quarterfinals







