San Francisco 49ers vs Carolina Panthers: Prediction, Head-to-Head, Odds & Stats (Tue, 25 Nov '25)
Wojtek Kolan
Published on 25 Nov, 01:15 AM UTC
Next Match 25/11/25 at 01:15 AM
San Francisco 49ers vs Carolina Panthers
📍 Levi's Stadium, USA.
Scheduled H2H Match For San Francisco 49ers Vs Carolina Panthers
NFL
Tue, 25 Nov 2025 at 01:15 AM UTC
San Francisco 49ers
USA
Recent Form
L
W
L
W
L
4
Win
Last 10 Played
10
0 Draws6
Win
14
Position
17
Kyle Shanahan
Manager
Dave Canales
Carolina Panthers
USA
Recent Form
W
W
L
W
L
4
Win
Last 10 Played
10
0 Draws6
Win
14
Position
17
Kyle Shanahan
Manager
Dave Canales
Game Schedule - Time Of Fixture
San Francisco 49ers will square off vs Carolina Panthers in NFL on Tue, 25 Nov 2025 at 01:15 AM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.
San Francisco 49ers vs Carolina Panthers H2H Results Summary
Analyzing the last 10 head-2-head games between these rivals, San Francisco 49ers have got the victory 4 times and Carolina Panthers have got the victory on 6 occasion. In the last match between them, San Francisco 49ers won 15-37.
| Head-to-Head (Last 10 Matches) | |
|---|---|
| San Francisco 49ers | 4 |
| Carolina Panthers | 6 |
San Francisco 49ers vs Carolina Panthers Past H2H Matches
NFL
08:05 PM
09/10/22
09/10/22
Carolina Panthers
15
San Francisco 49ers
37
08:05 PM
27/10/19
27/10/19
San Francisco 49ers
51
Carolina Panthers
13
08:25 PM
10/09/17
10/09/17
San Francisco 49ers
3
Carolina Panthers
23
05:00 PM
18/09/16
18/09/16
Carolina Panthers
46
San Francisco 49ers
27
06:05 PM
12/01/14
12/01/14
Carolina Panthers
10
San Francisco 49ers
23
09:05 PM
10/11/13
10/11/13
San Francisco 49ers
9
Carolina Panthers
10
05:00 PM
24/10/10
24/10/10
Carolina Panthers
23
San Francisco 49ers
20
06:00 PM
02/12/07
02/12/07
Carolina Panthers
31
San Francisco 49ers
14
09:15 PM
14/11/04
14/11/04
San Francisco 49ers
27
Carolina Panthers
37
06:00 PM
18/11/01
18/11/01
Carolina Panthers
22
San Francisco 49ers
25
06:00 PM
08/10/01
08/10/01
San Francisco 49ers
24
Carolina Panthers
14
San Francisco 49ers Recent Matches
NFL (27 Matches)
09:05 PM
16/11/25
16/11/25
Arizona Cardinals
22
San Francisco 49ers
41
W
09:25 PM
09/11/25
09/11/25
San Francisco 49ers
26
Los Angeles Rams
42
L
06:00 PM
02/11/25
02/11/25
New York Giants
24
San Francisco 49ers
34
W
05:00 PM
26/10/25
26/10/25
Houston Texans
26
San Francisco 49ers
15
L
12:20 AM
20/10/25
20/10/25
San Francisco 49ers
20
Atlanta Falcons
10
W
08:25 PM
12/10/25
12/10/25
Tampa Bay Buccaneers
30
San Francisco 49ers
19
L
12:15 AM
03/10/25
03/10/25
Los Angeles Rams
23
San Francisco 49ers
26
W
08:05 PM
28/09/25
28/09/25
San Francisco 49ers
21
Jacksonville Jaguars
26
L
08:25 PM
21/09/25
21/09/25
San Francisco 49ers
16
Arizona Cardinals
15
W
05:00 PM
14/09/25
14/09/25
New Orleans Saints
21
San Francisco 49ers
26
W
08:05 PM
07/09/25
07/09/25
Seattle Seahawks
13
San Francisco 49ers
17
W
09:25 PM
05/01/25
05/01/25
Arizona Cardinals
47
San Francisco 49ers
24
L
01:15 AM
31/12/24
31/12/24
San Francisco 49ers
34
Detroit Lions
40
L
09:25 PM
22/12/24
22/12/24
Miami Dolphins
29
San Francisco 49ers
17
L
01:15 AM
13/12/24
13/12/24
San Francisco 49ers
6
Los Angeles Rams
12
L
09:25 PM
08/12/24
08/12/24
San Francisco 49ers
38
Chicago Bears
13
W
01:20 AM
02/12/24
02/12/24
Buffalo Bills
35
San Francisco 49ers
10
L
09:25 PM
24/11/24
24/11/24
Green Bay Packers
38
San Francisco 49ers
10
L
09:05 PM
17/11/24
17/11/24
San Francisco 49ers
17
Seattle Seahawks
20
L
06:00 PM
10/11/24
10/11/24
Tampa Bay Buccaneers
20
San Francisco 49ers
23
W
12:20 AM
28/10/24
28/10/24
San Francisco 49ers
30
Dallas Cowboys
24
W
08:25 PM
20/10/24
20/10/24
San Francisco 49ers
18
Kansas City Chiefs
28
L
12:15 AM
11/10/24
11/10/24
Seattle Seahawks
24
San Francisco 49ers
36
W
08:05 PM
06/10/24
06/10/24
San Francisco 49ers
23
Arizona Cardinals
24
L
08:05 PM
29/09/24
29/09/24
San Francisco 49ers
30
New England Patriots
13
W
08:25 PM
22/09/24
22/09/24
Los Angeles Rams
27
San Francisco 49ers
24
L
05:00 PM
15/09/24
15/09/24
Minnesota Vikings
23
San Francisco 49ers
17
L
NFL Preseason (3 Matches)
12:30 AM
24/08/25
24/08/25
San Francisco 49ers
30
Los Angeles Chargers
23
W
08:00 PM
16/08/25
16/08/25
Las Vegas Raiders
19
San Francisco 49ers
22
W
12:30 AM
10/08/25
10/08/25
San Francisco 49ers
9
Denver Broncos
30
L
Carolina Panthers Recent Matches
NFL (27 Matches)
06:00 PM
16/11/25
16/11/25
Atlanta Falcons
27
Carolina Panthers
30
W
06:00 PM
09/11/25
09/11/25
Carolina Panthers
7
New Orleans Saints
17
L
06:00 PM
02/11/25
02/11/25
Green Bay Packers
13
Carolina Panthers
16
W
05:00 PM
26/10/25
26/10/25
Carolina Panthers
9
Buffalo Bills
40
L
05:00 PM
19/10/25
19/10/25
New York Jets
6
Carolina Panthers
13
W
05:00 PM
12/10/25
12/10/25
Carolina Panthers
30
Dallas Cowboys
27
W
05:00 PM
05/10/25
05/10/25
Carolina Panthers
27
Miami Dolphins
24
W
05:00 PM
28/09/25
28/09/25
New England Patriots
42
Carolina Panthers
13
L
05:00 PM
21/09/25
21/09/25
Carolina Panthers
30
Atlanta Falcons
0
W
08:05 PM
14/09/25
14/09/25
Arizona Cardinals
27
Carolina Panthers
22
L
05:00 PM
07/09/25
07/09/25
Jacksonville Jaguars
26
Carolina Panthers
10
L
06:00 PM
05/01/25
05/01/25
Atlanta Falcons
38
Carolina Panthers
44
W
06:00 PM
29/12/24
29/12/24
Tampa Bay Buccaneers
48
Carolina Panthers
14
L
06:00 PM
22/12/24
22/12/24
Carolina Panthers
36
Arizona Cardinals
30
W
06:00 PM
15/12/24
15/12/24
Carolina Panthers
14
Dallas Cowboys
30
L
06:00 PM
08/12/24
08/12/24
Philadelphia Eagles
22
Carolina Panthers
16
L
09:05 PM
01/12/24
01/12/24
Carolina Panthers
23
Tampa Bay Buccaneers
26
L
06:00 PM
24/11/24
24/11/24
Carolina Panthers
27
Kansas City Chiefs
30
L
02:30 PM
10/11/24
10/11/24
Carolina Panthers
20
New York Giants
17
W
06:00 PM
03/11/24
03/11/24
Carolina Panthers
23
New Orleans Saints
22
W
08:25 PM
27/10/24
27/10/24
Denver Broncos
28
Carolina Panthers
14
L
08:05 PM
20/10/24
20/10/24
Washington Commanders
40
Carolina Panthers
7
L
08:25 PM
13/10/24
13/10/24
Carolina Panthers
20
Atlanta Falcons
38
L
05:00 PM
06/10/24
06/10/24
Chicago Bears
36
Carolina Panthers
10
L
05:00 PM
29/09/24
29/09/24
Carolina Panthers
24
Cincinnati Bengals
34
L
08:05 PM
22/09/24
22/09/24
Las Vegas Raiders
22
Carolina Panthers
36
W
05:00 PM
15/09/24
15/09/24
Carolina Panthers
3
Los Angeles Chargers
26
L
NFL Preseason (3 Matches)
11:00 PM
21/08/25
21/08/25
Carolina Panthers
10
Pittsburgh Steelers
19
L
05:00 PM
16/08/25
16/08/25
Houston Texans
20
Carolina Panthers
3
L
11:00 PM
08/08/25
08/08/25
Carolina Panthers
10
Cleveland Browns
30
L
San Francisco 49ers Next Fixtures
NFL
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Cleveland Browns
San Francisco 49ers
Prediction
09:25 PM
14/12/25
14/12/25
San Francisco 49ers
Tennessee Titans
Prediction
01:15 AM
23/12/25
23/12/25
Indianapolis Colts
San Francisco 49ers
Prediction
01:20 AM
29/12/25
29/12/25
San Francisco 49ers
Chicago Bears
Prediction
06:00 PM
04/01/26
04/01/26
San Francisco 49ers
Seattle Seahawks
Prediction
Carolina Panthers Next Fixtures
NFL
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Carolina Panthers
Los Angeles Rams
Prediction
09:25 PM
14/12/25
14/12/25
New Orleans Saints
Carolina Panthers
Prediction
06:00 PM
21/12/25
21/12/25
Carolina Panthers
Tampa Bay Buccaneers
Prediction
06:00 PM
28/12/25
28/12/25
Carolina Panthers
Seattle Seahawks
Prediction
06:00 PM
04/01/26
04/01/26
Tampa Bay Buccaneers
Carolina Panthers
Prediction
San Francisco 49ers Last Match Played stats
Arizona Cardinals vs San Francisco 49ers
Final Score :22 - 41
| (H) | Offense | (A) |
|---|---|---|
| 3 | Touchdowns | 5 |
| 1/2 | Field goals | 3/3 |
| 488 | Total yards | 281 |
| 3 | Turnovers | 0 |
| 3/5 | Red zone efficiency | 4/5 |
| 34:15 | Time of Possession | 25:45 |
| 24 | First downs | 24 |
| 3 | First downs by penalty | 1 |
| 6/14 (42%) | Third down efficiency | 3/9 (33%) |
| 3 | Punts | 3 |
| 40.7 | Average yards per punt | 46.3 |
| 6.9 | Average yards per play | 5.4 |
| (H) | Passing | (A) |
| 18 | First downs by passing | 13 |
| 452 | Net yards passing | 186 |
| 452 | Gross yards passing | 200 |
| 2 | Passing touchdowns | 3 |
| 2 | Interceptions thrown | 0 |
| 7.9 | Average passing yards per attempt | 6.9 |
| 10 | Red zone passing attempts | 6 |
| (H) | Rushing | (A) |
| 14 | Rushing attempts | 25 |
| 36 | Rushing yards | 95 |
| 2.6 | Average rushing yards per attempt | 3.8 |
| 5 | First downs by rushing | 8 |
| 4 | Red zone rushing attempts | 4 |
| (H) | Other | (A) |
| 17 | Penalties | 1 |
| 130 | Yards penalized | 15 |
| 1 | Fumbles | 0 |
| 1 | Fumbles lost | 0 |
Carolina Panthers Last Match Played stats
Atlanta Falcons vs Carolina Panthers
Final Score :27 - 30
| (H) | Offense | (A) |
|---|---|---|
| 3 | Touchdowns | 3 |
| 2/2 | Field goals | 3/3 |
| 348 | Total yards | 486 |
| 1 | Turnovers | 0 |
| 3/3 | Red zone efficiency | 2/6 |
| 27:43 | Time of Possession | 37:07 |
| 23 | First downs | 22 |
| 0 | First downs by penalty | 4 |
| 4/11 (36%) | Third down efficiency | 6/17 (35%) |
| 5 | Punts | 3 |
| 51 | Average yards per punt | 46.7 |
| 6 | Average yards per play | 6.5 |
| (H) | Passing | (A) |
| 11 | First downs by passing | 20 |
| 223 | Net yards passing | 419 |
| 223 | Gross yards passing | 448 |
| 0 | Passing touchdowns | 3 |
| 0 | Interceptions thrown | 0 |
| 7.4 | Average passing yards per attempt | 8.4 |
| 1 | Red zone passing attempts | 9 |
| (H) | Rushing | (A) |
| 28 | Rushing attempts | 25 |
| 125 | Rushing yards | 67 |
| 4.5 | Average rushing yards per attempt | 2.7 |
| 8 | First downs by rushing | 2 |
| 4 | Red zone rushing attempts | 8 |
| (H) | Other | (A) |
| 6 | Penalties | 8 |
| 44 | Yards penalized | 49 |
| 3 | Fumbles | 0 |
| 1 | Fumbles lost | 0 |
NFL 25/26 Standings
| POS | TEAM | MP | W | L | D | PTS |
|---|---|---|---|---|---|---|
| 1 | 11 | 9 | 2 | 0 | 0.818 | |
| 2 | 11 | 9 | 2 | 0 | 0.818 | |
| 3 | 10 | 8 | 2 | 0 | 0.8 | |
| 4 | 10 | 8 | 2 | 0 | 0.8 | |
| 5 | 10 | 8 | 2 | 0 | 0.8 | |
| 6 | 10 | 7 | 3 | 0 | 0.7 | |
| 7 | 10 | 7 | 3 | 0 | 0.7 | |
| 8 | 10 | 7 | 3 | 0 | 0.7 | |
| 9 | 10 | 6 | 3 | 1 | 0.65 | |
| 10 | 11 | 7 | 4 | 0 | 0.636 | |
| 11 | 11 | 7 | 4 | 0 | 0.636 | |
| 12 | 10 | 6 | 4 | 0 | 0.6 | |
| 13 | 10 | 6 | 4 | 0 | 0.6 | |
| 14 | 10 | 6 | 4 | 0 | 0.6 | |
| 15 | 10 | 6 | 4 | 0 | 0.6 | |
| 16 | 11 | 6 | 5 | 0 | 0.545 | |
| 17 | 10 | 5 | 5 | 0 | 0.5 | |
| 18 | 10 | 5 | 5 | 0 | 0.5 | |
| 19 | 10 | 5 | 5 | 0 | 0.5 | |
| 20 | 10 | 4 | 5 | 1 | 0.45 | |
| 21 | 10 | 4 | 6 | 0 | 0.4 | |
| 22 | 11 | 4 | 7 | 0 | 0.364 | |
| 23 | 10 | 3 | 7 | 0 | 0.3 | |
| 24 | 10 | 3 | 7 | 0 | 0.3 | |
| 25 | 10 | 3 | 7 | 0 | 0.3 | |
| 26 | 11 | 3 | 8 | 0 | 0.273 | |
| 27 | 10 | 2 | 8 | 0 | 0.2 | |
| 28 | 10 | 2 | 8 | 0 | 0.2 | |
| 29 | 10 | 2 | 8 | 0 | 0.2 | |
| 30 | 10 | 2 | 8 | 0 | 0.2 | |
| 31 | 11 | 2 | 9 | 0 | 0.182 | |
| 32 | 10 | 1 | 9 | 0 | 0.1 |