Indianapolis Colts vs San Francisco 49ers: Prediction, Head-to-Head, Odds & Stats (Tue, 23 Dec '25)
Wojtek Kolan
Published on 23 Dec, 01:15 AM UTC
Next Match 23/12/25 at 01:15 AM
Indianapolis Colts vs San Francisco 49ers
📍 Lucas Oil Stadium, USA.
Scheduled H2H Match For Indianapolis Colts Vs San Francisco 49ers
NFL
Tue, 23 Dec 2025 at 01:15 AM UTC
Indianapolis Colts
USA
Recent Form
W
W
W
L
3
Win
Played
4
0 Draws1
Win
9
Position
6
Shane Steichen
Manager
Kyle Shanahan
San Francisco 49ers
USA
Recent Form
W
W
W
L
3
Win
Played
4
0 Draws1
Win
9
Position
6
Shane Steichen
Manager
Kyle Shanahan
Game Schedule - Time Of Fixture
Indianapolis Colts will square off vs San Francisco 49ers in NFL on Tue, 23 Dec 2025 at 01:15 AM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.
Indianapolis Colts vs San Francisco 49ers H2H Game Summary
For the most recent 4 head to head fixtures between these competitors, Indianapolis Colts have come out on top 3 times and San Francisco 49ers have got the victory on 1 occasion. In the last fixture between them, Indianapolis Colts won 18-30.
| Head-to-Head | Match Wins |
|---|---|
| Indianapolis Colts | 3 |
| San Francisco 49ers | 1 |
Indianapolis Colts vs San Francisco 49ers Past H2H Matches
NFL
12:20 AM
25/10/21
25/10/21
San Francisco 49ers
18
Indianapolis Colts
30
05:00 PM
08/10/17
08/10/17
Indianapolis Colts
26
San Francisco 49ers
23
06:00 PM
25/11/01
25/11/01
Indianapolis Colts
21
San Francisco 49ers
40
NFL Preseason
08:30 PM
25/08/18
25/08/18
Indianapolis Colts
23
San Francisco 49ers
17
Indianapolis Colts Recent Matches
NFL (24 Matches)
08:05 PM
28/09/25
28/09/25
Los Angeles Rams
27
Indianapolis Colts
20
L
05:00 PM
21/09/25
21/09/25
Tennessee Titans
20
Indianapolis Colts
41
W
08:05 PM
14/09/25
14/09/25
Indianapolis Colts
29
Denver Broncos
28
W
05:00 PM
07/09/25
07/09/25
Indianapolis Colts
33
Miami Dolphins
8
W
06:00 PM
05/01/25
05/01/25
Indianapolis Colts
26
Jacksonville Jaguars
23
W
06:00 PM
29/12/24
29/12/24
New York Giants
45
Indianapolis Colts
33
L
06:00 PM
22/12/24
22/12/24
Indianapolis Colts
38
Tennessee Titans
30
W
09:25 PM
15/12/24
15/12/24
Denver Broncos
31
Indianapolis Colts
13
L
06:00 PM
01/12/24
01/12/24
New England Patriots
24
Indianapolis Colts
25
W
06:00 PM
24/11/24
24/11/24
Indianapolis Colts
6
Detroit Lions
24
L
06:00 PM
17/11/24
17/11/24
New York Jets
27
Indianapolis Colts
28
W
06:00 PM
10/11/24
10/11/24
Indianapolis Colts
20
Buffalo Bills
30
L
01:20 AM
04/11/24
04/11/24
Minnesota Vikings
21
Indianapolis Colts
13
L
05:00 PM
27/10/24
27/10/24
Houston Texans
23
Indianapolis Colts
20
L
05:00 PM
20/10/24
20/10/24
Indianapolis Colts
16
Miami Dolphins
10
W
05:00 PM
13/10/24
13/10/24
Tennessee Titans
17
Indianapolis Colts
20
W
05:00 PM
06/10/24
06/10/24
Jacksonville Jaguars
37
Indianapolis Colts
34
L
05:00 PM
29/09/24
29/09/24
Indianapolis Colts
27
Pittsburgh Steelers
24
W
05:00 PM
22/09/24
22/09/24
Indianapolis Colts
21
Chicago Bears
16
W
05:00 PM
15/09/24
15/09/24
Green Bay Packers
16
Indianapolis Colts
10
L
05:00 PM
08/09/24
08/09/24
Indianapolis Colts
27
Houston Texans
29
L
01:15 AM
07/01/24
07/01/24
Indianapolis Colts
19
Houston Texans
23
L
06:00 PM
31/12/23
31/12/23
Indianapolis Colts
23
Las Vegas Raiders
20
W
06:00 PM
24/12/23
24/12/23
Atlanta Falcons
29
Indianapolis Colts
10
L
NFL Preseason (6 Matches)
05:00 PM
23/08/25
23/08/25
Cincinnati Bengals
14
Indianapolis Colts
41
W
05:00 PM
16/08/25
16/08/25
Indianapolis Colts
19
Green Bay Packers
23
L
11:00 PM
07/08/25
07/08/25
Baltimore Ravens
24
Indianapolis Colts
16
L
12:00 AM
23/08/24
23/08/24
Cincinnati Bengals
14
Indianapolis Colts
27
W
11:00 PM
17/08/24
17/08/24
Indianapolis Colts
21
Arizona Cardinals
13
W
05:00 PM
11/08/24
11/08/24
Indianapolis Colts
30
Denver Broncos
34
L
San Francisco 49ers Recent Matches
NFL (24 Matches)
12:15 AM
03/10/25
03/10/25
Los Angeles Rams
23
San Francisco 49ers
26
W
08:05 PM
28/09/25
28/09/25
San Francisco 49ers
21
Jacksonville Jaguars
26
L
08:25 PM
21/09/25
21/09/25
San Francisco 49ers
16
Arizona Cardinals
15
W
05:00 PM
14/09/25
14/09/25
New Orleans Saints
21
San Francisco 49ers
26
W
08:05 PM
07/09/25
07/09/25
Seattle Seahawks
13
San Francisco 49ers
17
W
09:25 PM
05/01/25
05/01/25
Arizona Cardinals
47
San Francisco 49ers
24
L
01:15 AM
31/12/24
31/12/24
San Francisco 49ers
34
Detroit Lions
40
L
09:25 PM
22/12/24
22/12/24
Miami Dolphins
29
San Francisco 49ers
17
L
01:15 AM
13/12/24
13/12/24
San Francisco 49ers
6
Los Angeles Rams
12
L
09:25 PM
08/12/24
08/12/24
San Francisco 49ers
38
Chicago Bears
13
W
01:20 AM
02/12/24
02/12/24
Buffalo Bills
35
San Francisco 49ers
10
L
09:25 PM
24/11/24
24/11/24
Green Bay Packers
38
San Francisco 49ers
10
L
09:05 PM
17/11/24
17/11/24
San Francisco 49ers
17
Seattle Seahawks
20
L
06:00 PM
10/11/24
10/11/24
Tampa Bay Buccaneers
20
San Francisco 49ers
23
W
12:20 AM
28/10/24
28/10/24
San Francisco 49ers
30
Dallas Cowboys
24
W
08:25 PM
20/10/24
20/10/24
San Francisco 49ers
18
Kansas City Chiefs
28
L
12:15 AM
11/10/24
11/10/24
Seattle Seahawks
24
San Francisco 49ers
36
W
08:05 PM
06/10/24
06/10/24
San Francisco 49ers
23
Arizona Cardinals
24
L
08:05 PM
29/09/24
29/09/24
San Francisco 49ers
30
New England Patriots
13
W
08:25 PM
22/09/24
22/09/24
Los Angeles Rams
27
San Francisco 49ers
24
L
05:00 PM
15/09/24
15/09/24
Minnesota Vikings
23
San Francisco 49ers
17
L
12:15 AM
10/09/24
10/09/24
San Francisco 49ers
32
New York Jets
19
W
11:30 PM
11/02/24
11/02/24
Kansas City Chiefs
25
San Francisco 49ers
22
L
11:30 PM
28/01/24
28/01/24
San Francisco 49ers
34
Detroit Lions
31
W
NFL Preseason (6 Matches)
12:30 AM
24/08/25
24/08/25
San Francisco 49ers
30
Los Angeles Chargers
23
W
08:00 PM
16/08/25
16/08/25
Las Vegas Raiders
19
San Francisco 49ers
22
W
12:30 AM
10/08/25
10/08/25
San Francisco 49ers
9
Denver Broncos
30
L
02:00 AM
24/08/24
24/08/24
Las Vegas Raiders
24
San Francisco 49ers
24
D
12:00 AM
19/08/24
19/08/24
San Francisco 49ers
16
New Orleans Saints
10
W
11:00 PM
10/08/24
10/08/24
Tennessee Titans
17
San Francisco 49ers
13
L
Indianapolis Colts Next Fixtures
NFL
05:00 PM
05/10/25
05/10/25
Indianapolis Colts
Las Vegas Raiders
Prediction
05:00 PM
12/10/25
12/10/25
Indianapolis Colts
Arizona Cardinals
Prediction
08:05 PM
19/10/25
19/10/25
Los Angeles Chargers
Indianapolis Colts
Prediction
08:25 PM
26/10/25
26/10/25
Indianapolis Colts
Tennessee Titans
Prediction
06:00 PM
02/11/25
02/11/25
Pittsburgh Steelers
Indianapolis Colts
Prediction
02:30 PM
09/11/25
09/11/25
Indianapolis Colts
Atlanta Falcons
Prediction
06:00 PM
23/11/25
23/11/25
Kansas City Chiefs
Indianapolis Colts
Prediction
06:00 PM
30/11/25
30/11/25
Indianapolis Colts
Houston Texans
Prediction
06:00 PM
07/12/25
07/12/25
Jacksonville Jaguars
Indianapolis Colts
Prediction
09:25 PM
14/12/25
14/12/25
Seattle Seahawks
Indianapolis Colts
Prediction
01:15 AM
23/12/25
23/12/25
Indianapolis Colts
San Francisco 49ers
Prediction
06:00 PM
28/12/25
28/12/25
Indianapolis Colts
Jacksonville Jaguars
Prediction
06:00 PM
04/01/26
04/01/26
Houston Texans
Indianapolis Colts
Prediction
San Francisco 49ers Next Fixtures
NFL
08:25 PM
12/10/25
12/10/25
Tampa Bay Buccaneers
San Francisco 49ers
Prediction
12:20 AM
20/10/25
20/10/25
San Francisco 49ers
Atlanta Falcons
Prediction
05:00 PM
26/10/25
26/10/25
Houston Texans
San Francisco 49ers
Prediction
06:00 PM
02/11/25
02/11/25
New York Giants
San Francisco 49ers
Prediction
09:25 PM
09/11/25
09/11/25
San Francisco 49ers
Los Angeles Rams
Prediction
09:05 PM
16/11/25
16/11/25
Arizona Cardinals
San Francisco 49ers
Prediction
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Cleveland Browns
San Francisco 49ers
Prediction
09:25 PM
14/12/25
14/12/25
San Francisco 49ers
Tennessee Titans
Prediction
01:15 AM
23/12/25
23/12/25
Indianapolis Colts
San Francisco 49ers
Prediction
01:20 AM
29/12/25
29/12/25
San Francisco 49ers
Chicago Bears
Prediction
06:00 PM
04/01/26
04/01/26
San Francisco 49ers
Seattle Seahawks
Prediction
Indianapolis Colts Last Match Played Scorecard Stats
Scorecard Not Available For This Match
San Francisco 49ers Last Match Played Scorecard Stats
Scorecard Not Available For This Match
NFL 25/26 Standings
| POS | TEAM | MP | W | L | PTS |
|---|---|---|---|---|---|
| 1 |  Philadelphia Eagles | 4 | 4 | 0 | 1 |
| 2 |  Buffalo Bills | 4 | 4 | 0 | 1 |
| 3 |  San Francisco 49ers | 5 | 4 | 1 | 0.8 |
| 4 |  Jacksonville Jaguars | 4 | 3 | 1 | 0.75 |
| 5 |  Seattle Seahawks | 4 | 3 | 1 | 0.75 |
| 6 |  Los Angeles Chargers | 4 | 3 | 1 | 0.75 |
| 7 |  Detroit Lions | 4 | 3 | 1 | 0.75 |
| 8 |  Pittsburgh Steelers | 4 | 3 | 1 | 0.75 |
| 9 |  Indianapolis Colts | 4 | 3 | 1 | 0.75 |
| 10 |  Tampa Bay Buccaneers | 4 | 3 | 1 | 0.75 |
| 11 |  Green Bay Packers | 4 | 2 | 1 | 0.625 |
| 12 |  Los Angeles Rams | 5 | 3 | 2 | 0.6 |
| 13 |  Minnesota Vikings | 4 | 2 | 2 | 0.5 |
| 14 |  Atlanta Falcons | 4 | 2 | 2 | 0.5 |
| 15 |  Cincinnati Bengals | 4 | 2 | 2 | 0.5 |
| 16 |  Chicago Bears | 4 | 2 | 2 | 0.5 |
| 17 |  Washington Commanders | 4 | 2 | 2 | 0.5 |
| 18 |  New England Patriots | 4 | 2 | 2 | 0.5 |
| 19 |  Kansas City Chiefs | 4 | 2 | 2 | 0.5 |
| 20 |  Denver Broncos | 4 | 2 | 2 | 0.5 |
| 21 |  Arizona Cardinals | 4 | 2 | 2 | 0.5 |
| 22 |  Dallas Cowboys | 4 | 1 | 2 | 0.375 |
| 23 |  New York Giants | 4 | 1 | 3 | 0.25 |
| 24 |  Cleveland Browns | 4 | 1 | 3 | 0.25 |
| 25 |  Las Vegas Raiders | 4 | 1 | 3 | 0.25 |
| 26 |  Carolina Panthers | 4 | 1 | 3 | 0.25 |
| 27 |  Baltimore Ravens | 4 | 1 | 3 | 0.25 |
| 28 |  Miami Dolphins | 4 | 1 | 3 | 0.25 |
| 29 |  Houston Texans | 4 | 1 | 3 | 0.25 |
| 30 |  New York Jets | 4 | 0 | 4 | 0 |
| 31 |  New Orleans Saints | 4 | 0 | 4 | 0 |
| 32 |  Tennessee Titans | 4 | 0 | 4 | 0 |
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