San Francisco 49ers vs Carolina Panthers: Prediction, Head-to-Head, Odds & Stats (Tue, 25 Nov '25)
Wojtek Kolan
Published on 25 Nov, 01:15 AM
Next Match 25/11/25 at 01:15 AM UTC
San Francisco 49ers vs Carolina Panthers
📍 Levi's Stadium, USA.
Scheduled H2H Match For San Francisco 49ers Vs Carolina Panthers
NFL
Tue, 25 Nov 2025 at 01:15 AM UTC
San Francisco 49ers
USA
Recent Form
W
L
W
L
W
4
Win
Last 10 Played
10
0 Draws6
Win
10
Position
18
Kyle Shanahan
Manager
Dave Canales
Carolina Panthers
USA
Recent Form
W
L
W
L
W
4
Win
Last 10 Played
10
0 Draws6
Win
10
Position
18
Kyle Shanahan
Manager
Dave Canales
Game Schedule - Time Of Fixture
San Francisco 49ers will square off vs Carolina Panthers in NFL on Tue, 25 Nov 2025 at 01:15 AM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.
San Francisco 49ers vs Carolina Panthers Forecast
Calculated from the implicit probability from the odds, San Francisco 49ers have a 78.55% to get the victory. Join the Matchstat.com predictions club to get data on implied vs our expert predictions to discover today’s highly profitable bets so you can make successful bets.
| Prediction | Chance to win |
|---|---|
| San Francisco 49ers | 78.55 % |
| Carolina Panthers | 25.06 % |
Above win % is implied from odds. Login / Signup to discover our expert predictions. | |
San Francisco 49ers vs Carolina Panthers H2H Match Summary
Over the last 10 H2H fixtures for these teams, San Francisco 49ers have won 4 times and Carolina Panthers have got the victory on 6 occasion. In the last fixture between them, San Francisco 49ers won 15-37.
| Head-to-Head (Last 10 Matches) | |
|---|---|
| San Francisco 49ers | 4 |
| Carolina Panthers | 6 |
Matchstat.com San Francisco 49ers vs Carolina Panthers Prediction For This Upcoming H2H Match
San Francisco 49ers vs Carolina Panthers Best Odds For The Match
Winner (incl. overtime)
1W
1.273
2W
3.99
San Francisco 49ers vs Carolina Panthers Premium Model Best Player Props Bets
Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AM
Christian McCaffrey Under 5.5 Receptions
Probability
Probability:62.95%
Edge
Edge:5.45%
Odds
Odds:-135
Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMTetairoa McMillan Under 5.5 Receptions
Probability
Probability:64.85%
Edge
Edge:4.85%
Odds
Odds:-150
This data is only Bookie Predictions.
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Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:5.35%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:8.3%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:8.4%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:4.35%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:3.7%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:8.05%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:8.4%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:5.4%
Odds
Odds:Panthers vs. 49ersPanthers vs. 49ers
.25 Nov 25 at 01:15 AMPanthers vs. 49ers
Probability
Probability:Edge
Edge:7.85%
Odds
Odds:San Francisco 49ers vs Carolina Panthers Past H2H Matches
NFL
08:05 PM
09/10/22
09/10/22
Carolina Panthers
15
San Francisco 49ers
37
08:05 PM
27/10/19
27/10/19
San Francisco 49ers
51
Carolina Panthers
13
08:25 PM
10/09/17
10/09/17
San Francisco 49ers
3
Carolina Panthers
23
05:00 PM
18/09/16
18/09/16
Carolina Panthers
46
San Francisco 49ers
27
06:05 PM
12/01/14
12/01/14
Carolina Panthers
10
San Francisco 49ers
23
09:05 PM
10/11/13
10/11/13
San Francisco 49ers
9
Carolina Panthers
10
05:00 PM
24/10/10
24/10/10
Carolina Panthers
23
San Francisco 49ers
20
06:00 PM
02/12/07
02/12/07
Carolina Panthers
31
San Francisco 49ers
14
09:15 PM
14/11/04
14/11/04
San Francisco 49ers
27
Carolina Panthers
37
06:00 PM
18/11/01
18/11/01
Carolina Panthers
22
San Francisco 49ers
25
06:00 PM
08/10/01
08/10/01
San Francisco 49ers
24
Carolina Panthers
14
San Francisco 49ers Recent Matches
NFL (27 Matches)
09:05 PM
16/11/25
16/11/25
Arizona Cardinals
22
San Francisco 49ers
41
W
09:25 PM
09/11/25
09/11/25
San Francisco 49ers
26
Los Angeles Rams
42
L
06:00 PM
02/11/25
02/11/25
New York Giants
24
San Francisco 49ers
34
W
05:00 PM
26/10/25
26/10/25
Houston Texans
26
San Francisco 49ers
15
L
12:20 AM
20/10/25
20/10/25
San Francisco 49ers
20
Atlanta Falcons
10
W
08:25 PM
12/10/25
12/10/25
Tampa Bay Buccaneers
30
San Francisco 49ers
19
L
12:15 AM
03/10/25
03/10/25
Los Angeles Rams
23
San Francisco 49ers
26
W
08:05 PM
28/09/25
28/09/25
San Francisco 49ers
21
Jacksonville Jaguars
26
L
08:25 PM
21/09/25
21/09/25
San Francisco 49ers
16
Arizona Cardinals
15
W
05:00 PM
14/09/25
14/09/25
New Orleans Saints
21
San Francisco 49ers
26
W
08:05 PM
07/09/25
07/09/25
Seattle Seahawks
13
San Francisco 49ers
17
W
09:25 PM
05/01/25
05/01/25
Arizona Cardinals
47
San Francisco 49ers
24
L
01:15 AM
31/12/24
31/12/24
San Francisco 49ers
34
Detroit Lions
40
L
09:25 PM
22/12/24
22/12/24
Miami Dolphins
29
San Francisco 49ers
17
L
01:15 AM
13/12/24
13/12/24
San Francisco 49ers
6
Los Angeles Rams
12
L
09:25 PM
08/12/24
08/12/24
San Francisco 49ers
38
Chicago Bears
13
W
01:20 AM
02/12/24
02/12/24
Buffalo Bills
35
San Francisco 49ers
10
L
09:25 PM
24/11/24
24/11/24
Green Bay Packers
38
San Francisco 49ers
10
L
09:05 PM
17/11/24
17/11/24
San Francisco 49ers
17
Seattle Seahawks
20
L
06:00 PM
10/11/24
10/11/24
Tampa Bay Buccaneers
20
San Francisco 49ers
23
W
12:20 AM
28/10/24
28/10/24
San Francisco 49ers
30
Dallas Cowboys
24
W
08:25 PM
20/10/24
20/10/24
San Francisco 49ers
18
Kansas City Chiefs
28
L
12:15 AM
11/10/24
11/10/24
Seattle Seahawks
24
San Francisco 49ers
36
W
08:05 PM
06/10/24
06/10/24
San Francisco 49ers
23
Arizona Cardinals
24
L
08:05 PM
29/09/24
29/09/24
San Francisco 49ers
30
New England Patriots
13
W
08:25 PM
22/09/24
22/09/24
Los Angeles Rams
27
San Francisco 49ers
24
L
05:00 PM
15/09/24
15/09/24
Minnesota Vikings
23
San Francisco 49ers
17
L
NFL Preseason (3 Matches)
12:30 AM
24/08/25
24/08/25
San Francisco 49ers
30
Los Angeles Chargers
23
W
08:00 PM
16/08/25
16/08/25
Las Vegas Raiders
19
San Francisco 49ers
22
W
12:30 AM
10/08/25
10/08/25
San Francisco 49ers
9
Denver Broncos
30
L
Carolina Panthers Recent Matches
NFL (27 Matches)
06:00 PM
16/11/25
16/11/25
Atlanta Falcons
27
Carolina Panthers
30
W
06:00 PM
09/11/25
09/11/25
Carolina Panthers
7
New Orleans Saints
17
L
06:00 PM
02/11/25
02/11/25
Green Bay Packers
13
Carolina Panthers
16
W
05:00 PM
26/10/25
26/10/25
Carolina Panthers
9
Buffalo Bills
40
L
05:00 PM
19/10/25
19/10/25
New York Jets
6
Carolina Panthers
13
W
05:00 PM
12/10/25
12/10/25
Carolina Panthers
30
Dallas Cowboys
27
W
05:00 PM
05/10/25
05/10/25
Carolina Panthers
27
Miami Dolphins
24
W
05:00 PM
28/09/25
28/09/25
New England Patriots
42
Carolina Panthers
13
L
05:00 PM
21/09/25
21/09/25
Carolina Panthers
30
Atlanta Falcons
0
W
08:05 PM
14/09/25
14/09/25
Arizona Cardinals
27
Carolina Panthers
22
L
05:00 PM
07/09/25
07/09/25
Jacksonville Jaguars
26
Carolina Panthers
10
L
06:00 PM
05/01/25
05/01/25
Atlanta Falcons
38
Carolina Panthers
44
W
06:00 PM
29/12/24
29/12/24
Tampa Bay Buccaneers
48
Carolina Panthers
14
L
06:00 PM
22/12/24
22/12/24
Carolina Panthers
36
Arizona Cardinals
30
W
06:00 PM
15/12/24
15/12/24
Carolina Panthers
14
Dallas Cowboys
30
L
06:00 PM
08/12/24
08/12/24
Philadelphia Eagles
22
Carolina Panthers
16
L
09:05 PM
01/12/24
01/12/24
Carolina Panthers
23
Tampa Bay Buccaneers
26
L
06:00 PM
24/11/24
24/11/24
Carolina Panthers
27
Kansas City Chiefs
30
L
02:30 PM
10/11/24
10/11/24
Carolina Panthers
20
New York Giants
17
W
06:00 PM
03/11/24
03/11/24
Carolina Panthers
23
New Orleans Saints
22
W
08:25 PM
27/10/24
27/10/24
Denver Broncos
28
Carolina Panthers
14
L
08:05 PM
20/10/24
20/10/24
Washington Commanders
40
Carolina Panthers
7
L
08:25 PM
13/10/24
13/10/24
Carolina Panthers
20
Atlanta Falcons
38
L
05:00 PM
06/10/24
06/10/24
Chicago Bears
36
Carolina Panthers
10
L
05:00 PM
29/09/24
29/09/24
Carolina Panthers
24
Cincinnati Bengals
34
L
08:05 PM
22/09/24
22/09/24
Las Vegas Raiders
22
Carolina Panthers
36
W
05:00 PM
15/09/24
15/09/24
Carolina Panthers
3
Los Angeles Chargers
26
L
NFL Preseason (3 Matches)
11:00 PM
21/08/25
21/08/25
Carolina Panthers
10
Pittsburgh Steelers
19
L
05:00 PM
16/08/25
16/08/25
Houston Texans
20
Carolina Panthers
3
L
11:00 PM
08/08/25
08/08/25
Carolina Panthers
10
Cleveland Browns
30
L
San Francisco 49ers Next Fixtures
NFL
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Cleveland Browns
San Francisco 49ers
Prediction
09:25 PM
14/12/25
14/12/25
San Francisco 49ers
Tennessee Titans
Prediction
01:15 AM
23/12/25
23/12/25
Indianapolis Colts
San Francisco 49ers
Prediction
01:20 AM
29/12/25
29/12/25
San Francisco 49ers
Chicago Bears
Prediction
06:00 PM
04/01/26
04/01/26
San Francisco 49ers
Seattle Seahawks
Prediction
Carolina Panthers Next Fixtures
NFL
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Carolina Panthers
Los Angeles Rams
Prediction
09:25 PM
14/12/25
14/12/25
New Orleans Saints
Carolina Panthers
Prediction
06:00 PM
21/12/25
21/12/25
Carolina Panthers
Tampa Bay Buccaneers
Prediction
06:00 PM
28/12/25
28/12/25
Carolina Panthers
Seattle Seahawks
Prediction
06:00 PM
04/01/26
04/01/26
Tampa Bay Buccaneers
Carolina Panthers
Prediction
San Francisco 49ers Last Match Played stats
Arizona Cardinals vs San Francisco 49ers
Final Score :22 - 41
| (H) | Offense | (A) |
|---|---|---|
| 3 | Touchdowns | 5 |
| 1/2 | Field goals | 3/3 |
| 488 | Total yards | 281 |
| 3 | Turnovers | 0 |
| 3/5 | Red zone efficiency | 4/5 |
| 34:15 | Time of Possession | 25:45 |
| 24 | First downs | 24 |
| 3 | First downs by penalty | 1 |
| 6/14 (42%) | Third down efficiency | 3/9 (33%) |
| 3 | Punts | 3 |
| 40.7 | Average yards per punt | 46.3 |
| 6.9 | Average yards per play | 5.4 |
| (H) | Passing | (A) |
| 18 | First downs by passing | 13 |
| 452 | Net yards passing | 186 |
| 452 | Gross yards passing | 200 |
| 2 | Passing touchdowns | 3 |
| 2 | Interceptions thrown | 0 |
| 7.9 | Average passing yards per attempt | 6.9 |
| 10 | Red zone passing attempts | 6 |
| (H) | Rushing | (A) |
| 14 | Rushing attempts | 25 |
| 36 | Rushing yards | 95 |
| 2.6 | Average rushing yards per attempt | 3.8 |
| 5 | First downs by rushing | 8 |
| 4 | Red zone rushing attempts | 4 |
| (H) | Other | (A) |
| 17 | Penalties | 1 |
| 130 | Yards penalized | 15 |
| 1 | Fumbles | 0 |
| 1 | Fumbles lost | 0 |
Carolina Panthers Last Match Played stats
Atlanta Falcons vs Carolina Panthers
Final Score :27 - 30
| (H) | Offense | (A) |
|---|---|---|
| 3 | Touchdowns | 3 |
| 2/2 | Field goals | 3/3 |
| 348 | Total yards | 486 |
| 1 | Turnovers | 0 |
| 3/3 | Red zone efficiency | 2/6 |
| 27:43 | Time of Possession | 37:07 |
| 23 | First downs | 22 |
| 0 | First downs by penalty | 4 |
| 4/11 (36%) | Third down efficiency | 6/17 (35%) |
| 5 | Punts | 3 |
| 51 | Average yards per punt | 46.7 |
| 6 | Average yards per play | 6.5 |
| (H) | Passing | (A) |
| 11 | First downs by passing | 20 |
| 223 | Net yards passing | 419 |
| 223 | Gross yards passing | 448 |
| 0 | Passing touchdowns | 3 |
| 0 | Interceptions thrown | 0 |
| 7.4 | Average passing yards per attempt | 8.4 |
| 1 | Red zone passing attempts | 9 |
| (H) | Rushing | (A) |
| 28 | Rushing attempts | 25 |
| 125 | Rushing yards | 67 |
| 4.5 | Average rushing yards per attempt | 2.7 |
| 8 | First downs by rushing | 2 |
| 4 | Red zone rushing attempts | 8 |
| (H) | Other | (A) |
| 6 | Penalties | 8 |
| 44 | Yards penalized | 49 |
| 3 | Fumbles | 0 |
| 1 | Fumbles lost | 0 |
NFL 25/26 Standings
| POS | TEAM | MP | W | L | D | PTS |
|---|---|---|---|---|---|---|
| 1 | 12 | 10 | 2 | 0 | 0.833 | |
| 2 | 11 | 9 | 2 | 0 | 0.818 | |
| 3 | 11 | 9 | 2 | 0 | 0.818 | |
| 4 | 11 | 8 | 3 | 0 | 0.727 | |
| 5 | 11 | 8 | 3 | 0 | 0.727 | |
| 6 | 11 | 8 | 3 | 0 | 0.727 | |
| 7 | 11 | 8 | 3 | 0 | 0.727 | |
| 8 | 11 | 7 | 3 | 1 | 0.682 | |
| 9 | 11 | 7 | 4 | 0 | 0.636 | |
| 10 | 11 | 7 | 4 | 0 | 0.636 | |
| 11 | 11 | 7 | 4 | 0 | 0.636 | |
| 12 | 11 | 7 | 4 | 0 | 0.636 | |
| 13 | 11 | 7 | 4 | 0 | 0.636 | |
| 14 | 11 | 6 | 5 | 0 | 0.545 | |
| 15 | 11 | 6 | 5 | 0 | 0.545 | |
| 16 | 11 | 6 | 5 | 0 | 0.545 | |
| 17 | 11 | 6 | 5 | 0 | 0.545 | |
| 18 | 11 | 6 | 5 | 0 | 0.545 | |
| 19 | 11 | 6 | 5 | 0 | 0.545 | |
| 20 | 11 | 5 | 5 | 1 | 0.5 | |
| 21 | 11 | 4 | 7 | 0 | 0.364 | |
| 22 | 11 | 4 | 7 | 0 | 0.364 | |
| 23 | 11 | 4 | 7 | 0 | 0.364 | |
| 24 | 11 | 3 | 8 | 0 | 0.273 | |
| 25 | 11 | 3 | 8 | 0 | 0.273 | |
| 26 | 11 | 3 | 8 | 0 | 0.273 | |
| 27 | 11 | 3 | 8 | 0 | 0.273 | |
| 28 | 11 | 2 | 9 | 0 | 0.182 | |
| 29 | 11 | 2 | 9 | 0 | 0.182 | |
| 30 | 11 | 2 | 9 | 0 | 0.182 | |
| 31 | 12 | 2 | 10 | 0 | 0.167 | |
| 32 | 11 | 1 | 10 | 0 | 0.091 |
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