MLB Preview And Prediction: St. Louis Cardinals vs Athletics Betting Tips & Picks September 3, 2025

Who The Odds Favor: to get the victory

• Evaluating the odds for total points suggests there is a 78.99% prediction of this match having more than 5.5 total points scored:
  Match Over 5.5 Points → 1.27

  Prediction	Chance Of O/U (incl. EI) (5.5)
  Over	78.99 %
  Under	25.91 %
  Above is implied from odds. Login now to get our expert predictions.

• Evaluating the odds for points scored indicates there is a 40.65% prediction of this match having over 9.5 total points scored:
  Match Over 9.5 Points → 2.46

  Prediction	Chance Of O/U (incl. EI) (9.5)
  Over	40.65 %
  Under	62.42 %
  Above is calculated from odds. Login now to reveal our expert predictions.

• Derived via the sportsbook odds, Athletics are the favorite to cover the -1.5 handicap with extra innings included in this game, with a 68.49% chance of doing so. A solid prediction? Yes, because Sportsbooks produce sharp predictions:
  St. Louis Cardinals -1.5 Handicap → 2.92
  Athletics -1.5 Handicap → 1.46

  Prediction	Chance Of Handicap (incl. EI) (-1.5)
  St. Louis Cardinals	34.25 %
  Athletics	68.49 %
  Above is implied from odds. Login now to reveal our expert predictions.

• Calculated via the bookies odds, St. Louis Cardinals are the favorite to get the victory in regular time in this game with a 50% probability of winning. Is this accurate? Yes, because Bookies are skilled at predicting:
  St. Louis Cardinals Regular Time → 2.00
  Athletics Regular Time → 2.08
  Draw Regular Time → 9.40

  Prediction	Chance Of Reg. Time Result
  St. Louis Cardinals	50 %
  Athletics	48.08 %
  Draw	10.64 %
  Above is calculated from odds. Login now to discover our expert predictions.

• Analyzing the odds for total points implies there is a 100% prediction of this match having more than 4.5 total points:
  Match Over 4.5 Points → 1.00

  Prediction	Chance Of O/U (incl. EI) (4.5)
  Over	100 %
  Under	100 %
  Above is calculated from odds. Login now to find out our expert picks.

• Calculated from the bookies odds, Draw are the favorite to lead after the first inning in this fixture with a 52.36% chance of leading. An accurate tip? We think so, because Bookies are highly accurate:
  St. Louis Cardinals First Inning → 3.89
  Athletics First Inning → 3.68
  Draw First Inning → 1.91

  Prediction	Chance Of 1st Inning Result
  St. Louis Cardinals	25.71 %
  Athletics	27.17 %
  Draw	52.36 %
  Above is calculated from odds. Login now to find out our expert predictions.

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Prediction Based On Head-2-Head: Nip and tuck

Head To Head: St. Louis Cardinals (5 – 5) Athletics.
It’s Nip and tuck! Who’s got the edge? Analyzing the last 10 H2H fixtures between these two sides, both teams have the same number of victories. Our head-to-head data goes back to the encounter they had in 2004. This indicates that the scheduled game is a balanced contest. The last game happened on the Tue, 02 Sept 25, when St. Louis Cardinals achieved a 2 – 1 win.

Is this the decider? Both St. Louis Cardinals and Athletics have an equal H2H record. This upcoming clash will be a battle for dominance.

Current Form Prediction: Too close to call

Considering current performance before this fixture, St. Louis Cardinals got the win against Athletics with a score of 2-1. Athletics suffered a defeat up against St. Louis Cardinals with a result of 1-2. St. Louis Cardinals have got the victory in 5 of their last 10 matches vs all teams, whereas Athletics triumphed in 5 of their recent 10 matches versus all opponents, suggesting maybe this match is too close to call.

St. Louis Cardinals vs Athletics Best Sportsbook Odds For The Match

Winner (incl. extra innings)

1W

1.961

2W

1.961

Over Under (incl. extra innings)

> 5.5

1.266

< 5.5

3.86

> 9.5

2.46

< 9.5

1.602

> 4.5

1

< 4.5

1

Handicap (incl. extra innings) && -1.5

1W -1.5

2.92

2W -1.5

1.46

Regular Time Result

1W

2

2W

2.08

X

9.4

First Inning Result

1W

3.89

2W

3.68

X

1.91

St. Louis Cardinals vs Athletics Tips

Over Under (incl. extra innings) 4.5 → Over stands out as a worthwhile stake → 1.00