Arizona Cardinals vs San Francisco 49ers: Prediction, Head-to-Head, Odds & Stats (Sun, 16 Nov '25)
Wojtek Kolan
Published on 16 Nov, 09:05 PM UTC
Next Match 16/11/25 at 09:05 PM
Arizona Cardinals vs San Francisco 49ers
📍 State Farm Stadium, USA.
Scheduled H2H Match For Arizona Cardinals Vs San Francisco 49ers
NFL
Sun, 16 Nov 2025 at 09:05 PM UTC
Arizona Cardinals
USA
Recent Form
L
L
L
L
L
4
Win
Last 10 Played
10
0 Draws6
Win
26
Position
12
Jonathan Gannon
Manager
Kyle Shanahan
San Francisco 49ers
USA
Recent Form
L
W
L
W
L
4
Win
Last 10 Played
10
0 Draws6
Win
26
Position
12
Jonathan Gannon
Manager
Kyle Shanahan
Game Schedule - Time Of Fixture
Arizona Cardinals will square off vs San Francisco 49ers in NFL on Sun, 16 Nov 2025 at 09:05 PM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.
Arizona Cardinals vs San Francisco 49ers H2H Match Summary
For the most recent 10 H2H games for these teams, Arizona Cardinals have won 4 times and San Francisco 49ers have come out on top on 6 occasion. In the latest game between them, San Francisco 49ers won 16-15.
| Head-to-Head (Last 10 Matches) | |
|---|---|
| Arizona Cardinals | 4 |
| San Francisco 49ers | 6 |
Arizona Cardinals vs San Francisco 49ers Past H2H Matches
NFL
08:25 PM
21/09/25
21/09/25
San Francisco 49ers
16
Arizona Cardinals
15
09:25 PM
05/01/25
05/01/25
Arizona Cardinals
47
San Francisco 49ers
24
08:05 PM
06/10/24
06/10/24
San Francisco 49ers
23
Arizona Cardinals
24
09:05 PM
17/12/23
17/12/23
Arizona Cardinals
29
San Francisco 49ers
45
08:25 PM
01/10/23
01/10/23
San Francisco 49ers
35
Arizona Cardinals
16
09:25 PM
08/01/23
08/01/23
San Francisco 49ers
38
Arizona Cardinals
13
01:15 AM
22/11/22
22/11/22
Arizona Cardinals
10
San Francisco 49ers
38
09:25 PM
07/11/21
07/11/21
San Francisco 49ers
17
Arizona Cardinals
31
08:25 PM
10/10/21
10/10/21
Arizona Cardinals
17
San Francisco 49ers
10
09:30 PM
26/12/20
26/12/20
Arizona Cardinals
12
San Francisco 49ers
20
08:25 PM
13/09/20
13/09/20
San Francisco 49ers
20
Arizona Cardinals
24
09:05 PM
17/11/19
17/11/19
San Francisco 49ers
36
Arizona Cardinals
26
12:20 AM
01/11/19
01/11/19
Arizona Cardinals
25
San Francisco 49ers
28
08:25 PM
28/10/18
28/10/18
Arizona Cardinals
18
San Francisco 49ers
15
08:25 PM
07/10/18
07/10/18
San Francisco 49ers
18
Arizona Cardinals
28
09:05 PM
05/11/17
05/11/17
San Francisco 49ers
10
Arizona Cardinals
20
08:05 PM
01/10/17
01/10/17
Arizona Cardinals
18
San Francisco 49ers
15
09:25 PM
13/11/16
13/11/16
Arizona Cardinals
23
San Francisco 49ers
20
12:25 AM
07/10/16
07/10/16
San Francisco 49ers
21
Arizona Cardinals
33
09:05 PM
29/11/15
29/11/15
San Francisco 49ers
13
Arizona Cardinals
19
08:05 PM
27/09/15
27/09/15
Arizona Cardinals
47
San Francisco 49ers
7
09:25 PM
28/12/14
28/12/14
San Francisco 49ers
20
Arizona Cardinals
17
08:05 PM
21/09/14
21/09/14
Arizona Cardinals
23
San Francisco 49ers
14
09:25 PM
29/12/13
29/12/13
Arizona Cardinals
20
San Francisco 49ers
23
08:25 PM
13/10/13
13/10/13
San Francisco 49ers
32
Arizona Cardinals
20
09:25 PM
30/12/12
30/12/12
San Francisco 49ers
27
Arizona Cardinals
13
12:30 AM
30/10/12
30/10/12
Arizona Cardinals
3
San Francisco 49ers
24
09:05 PM
11/12/11
11/12/11
Arizona Cardinals
21
San Francisco 49ers
19
09:05 PM
20/11/11
20/11/11
San Francisco 49ers
23
Arizona Cardinals
7
09:15 PM
02/01/11
02/01/11
San Francisco 49ers
38
Arizona Cardinals
7
01:30 AM
30/11/10
30/11/10
Arizona Cardinals
6
San Francisco 49ers
27
01:30 AM
15/12/09
15/12/09
San Francisco 49ers
24
Arizona Cardinals
9
08:15 PM
13/09/09
13/09/09
Arizona Cardinals
16
San Francisco 49ers
20
01:30 AM
11/11/08
11/11/08
Arizona Cardinals
29
San Francisco 49ers
24
08:15 PM
07/09/08
07/09/08
San Francisco 49ers
13
Arizona Cardinals
23
09:05 PM
25/11/07
25/11/07
Arizona Cardinals
31
San Francisco 49ers
37
02:15 AM
11/09/07
11/09/07
San Francisco 49ers
20
Arizona Cardinals
17
09:05 PM
24/12/06
24/12/06
San Francisco 49ers
20
Arizona Cardinals
26
08:15 PM
10/09/06
10/09/06
Arizona Cardinals
34
San Francisco 49ers
27
09:05 PM
04/12/05
04/12/05
San Francisco 49ers
10
Arizona Cardinals
17
12:30 AM
03/10/05
03/10/05
Arizona Cardinals
31
San Francisco 49ers
14
09:15 PM
12/12/04
12/12/04
Arizona Cardinals
28
San Francisco 49ers
31
08:15 PM
10/10/04
10/10/04
San Francisco 49ers
31
Arizona Cardinals
28
09:05 PM
07/12/03
07/12/03
San Francisco 49ers
50
Arizona Cardinals
14
08:45 PM
26/10/03
26/10/03
Arizona Cardinals
16
San Francisco 49ers
13
10:00 PM
22/12/02
22/12/02
Arizona Cardinals
14
San Francisco 49ers
17
04:00 PM
27/11/02
27/11/02
San Francisco 49ers
38
Arizona Cardinals
28
Arizona Cardinals Recent Matches
NFL (24 Matches)
08:25 PM
19/10/25
19/10/25
Arizona Cardinals
23
Green Bay Packers
27
L
05:00 PM
12/10/25
12/10/25
Indianapolis Colts
31
Arizona Cardinals
27
L
08:05 PM
05/10/25
05/10/25
Arizona Cardinals
21
Tennessee Titans
22
L
12:15 AM
26/09/25
26/09/25
Arizona Cardinals
20
Seattle Seahawks
23
L
08:25 PM
21/09/25
21/09/25
San Francisco 49ers
16
Arizona Cardinals
15
L
08:05 PM
14/09/25
14/09/25
Arizona Cardinals
27
Carolina Panthers
22
W
05:00 PM
07/09/25
07/09/25
New Orleans Saints
13
Arizona Cardinals
20
W
09:25 PM
05/01/25
05/01/25
Arizona Cardinals
47
San Francisco 49ers
24
W
01:10 AM
29/12/24
29/12/24
Los Angeles Rams
13
Arizona Cardinals
9
L
06:00 PM
22/12/24
22/12/24
Carolina Panthers
36
Arizona Cardinals
30
L
09:25 PM
15/12/24
15/12/24
Arizona Cardinals
30
New England Patriots
17
W
09:05 PM
08/12/24
08/12/24
Arizona Cardinals
18
Seattle Seahawks
30
L
06:00 PM
01/12/24
01/12/24
Minnesota Vikings
23
Arizona Cardinals
22
L
09:25 PM
24/11/24
24/11/24
Seattle Seahawks
16
Arizona Cardinals
6
L
09:25 PM
10/11/24
10/11/24
Arizona Cardinals
31
New York Jets
6
W
09:05 PM
03/11/24
03/11/24
Arizona Cardinals
29
Chicago Bears
9
W
05:00 PM
27/10/24
27/10/24
Miami Dolphins
27
Arizona Cardinals
28
W
01:00 AM
22/10/24
22/10/24
Arizona Cardinals
17
Los Angeles Chargers
15
W
05:00 PM
13/10/24
13/10/24
Green Bay Packers
34
Arizona Cardinals
13
L
08:05 PM
06/10/24
06/10/24
San Francisco 49ers
23
Arizona Cardinals
24
W
08:05 PM
29/09/24
29/09/24
Arizona Cardinals
14
Washington Commanders
42
L
08:25 PM
22/09/24
22/09/24
Arizona Cardinals
13
Detroit Lions
20
L
08:05 PM
15/09/24
15/09/24
Arizona Cardinals
41
Los Angeles Rams
10
W
05:00 PM
08/09/24
08/09/24
Buffalo Bills
34
Arizona Cardinals
28
L
NFL Preseason (6 Matches)
02:00 AM
24/08/25
24/08/25
Arizona Cardinals
20
Las Vegas Raiders
10
W
01:30 AM
17/08/25
17/08/25
Denver Broncos
27
Arizona Cardinals
7
L
12:00 AM
10/08/25
10/08/25
Arizona Cardinals
20
Kansas City Chiefs
17
W
08:30 PM
25/08/24
25/08/24
Denver Broncos
38
Arizona Cardinals
12
L
11:00 PM
17/08/24
17/08/24
Indianapolis Colts
21
Arizona Cardinals
13
L
12:00 AM
11/08/24
11/08/24
Arizona Cardinals
14
New Orleans Saints
16
L
San Francisco 49ers Recent Matches
NFL (25 Matches)
05:00 PM
26/10/25
26/10/25
Houston Texans
26
San Francisco 49ers
15
L
12:20 AM
20/10/25
20/10/25
San Francisco 49ers
20
Atlanta Falcons
10
W
08:25 PM
12/10/25
12/10/25
Tampa Bay Buccaneers
30
San Francisco 49ers
19
L
12:15 AM
03/10/25
03/10/25
Los Angeles Rams
23
San Francisco 49ers
26
W
08:05 PM
28/09/25
28/09/25
San Francisco 49ers
21
Jacksonville Jaguars
26
L
08:25 PM
21/09/25
21/09/25
San Francisco 49ers
16
Arizona Cardinals
15
W
05:00 PM
14/09/25
14/09/25
New Orleans Saints
21
San Francisco 49ers
26
W
08:05 PM
07/09/25
07/09/25
Seattle Seahawks
13
San Francisco 49ers
17
W
09:25 PM
05/01/25
05/01/25
Arizona Cardinals
47
San Francisco 49ers
24
L
01:15 AM
31/12/24
31/12/24
San Francisco 49ers
34
Detroit Lions
40
L
09:25 PM
22/12/24
22/12/24
Miami Dolphins
29
San Francisco 49ers
17
L
01:15 AM
13/12/24
13/12/24
San Francisco 49ers
6
Los Angeles Rams
12
L
09:25 PM
08/12/24
08/12/24
San Francisco 49ers
38
Chicago Bears
13
W
01:20 AM
02/12/24
02/12/24
Buffalo Bills
35
San Francisco 49ers
10
L
09:25 PM
24/11/24
24/11/24
Green Bay Packers
38
San Francisco 49ers
10
L
09:05 PM
17/11/24
17/11/24
San Francisco 49ers
17
Seattle Seahawks
20
L
06:00 PM
10/11/24
10/11/24
Tampa Bay Buccaneers
20
San Francisco 49ers
23
W
12:20 AM
28/10/24
28/10/24
San Francisco 49ers
30
Dallas Cowboys
24
W
08:25 PM
20/10/24
20/10/24
San Francisco 49ers
18
Kansas City Chiefs
28
L
12:15 AM
11/10/24
11/10/24
Seattle Seahawks
24
San Francisco 49ers
36
W
08:05 PM
06/10/24
06/10/24
San Francisco 49ers
23
Arizona Cardinals
24
L
08:05 PM
29/09/24
29/09/24
San Francisco 49ers
30
New England Patriots
13
W
08:25 PM
22/09/24
22/09/24
Los Angeles Rams
27
San Francisco 49ers
24
L
05:00 PM
15/09/24
15/09/24
Minnesota Vikings
23
San Francisco 49ers
17
L
12:15 AM
10/09/24
10/09/24
San Francisco 49ers
32
New York Jets
19
W
NFL Preseason (5 Matches)
12:30 AM
24/08/25
24/08/25
San Francisco 49ers
30
Los Angeles Chargers
23
W
08:00 PM
16/08/25
16/08/25
Las Vegas Raiders
19
San Francisco 49ers
22
W
12:30 AM
10/08/25
10/08/25
San Francisco 49ers
9
Denver Broncos
30
L
02:00 AM
24/08/24
24/08/24
Las Vegas Raiders
24
San Francisco 49ers
24
D
12:00 AM
19/08/24
19/08/24
San Francisco 49ers
16
New Orleans Saints
10
W
Arizona Cardinals Next Fixtures
NFL
01:15 AM
04/11/25
04/11/25
Dallas Cowboys
Arizona Cardinals
Prediction
09:05 PM
09/11/25
09/11/25
Seattle Seahawks
Arizona Cardinals
Prediction
09:05 PM
16/11/25
16/11/25
Arizona Cardinals
San Francisco 49ers
Prediction
09:05 PM
23/11/25
23/11/25
Arizona Cardinals
Jacksonville Jaguars
Prediction
06:00 PM
30/11/25
30/11/25
Tampa Bay Buccaneers
Arizona Cardinals
Prediction
09:25 PM
07/12/25
07/12/25
Arizona Cardinals
Los Angeles Rams
Prediction
06:00 PM
14/12/25
14/12/25
Houston Texans
Arizona Cardinals
Prediction
09:05 PM
21/12/25
21/12/25
Arizona Cardinals
Atlanta Falcons
Prediction
06:00 PM
28/12/25
28/12/25
Cincinnati Bengals
Arizona Cardinals
Prediction
06:00 PM
04/01/26
04/01/26
Los Angeles Rams
Arizona Cardinals
Prediction
San Francisco 49ers Next Fixtures
NFL
06:00 PM
02/11/25
02/11/25
New York Giants
San Francisco 49ers
Prediction
09:25 PM
09/11/25
09/11/25
San Francisco 49ers
Los Angeles Rams
Prediction
09:05 PM
16/11/25
16/11/25
Arizona Cardinals
San Francisco 49ers
Prediction
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Cleveland Browns
San Francisco 49ers
Prediction
09:25 PM
14/12/25
14/12/25
San Francisco 49ers
Tennessee Titans
Prediction
01:15 AM
23/12/25
23/12/25
Indianapolis Colts
San Francisco 49ers
Prediction
01:20 AM
29/12/25
29/12/25
San Francisco 49ers
Chicago Bears
Prediction
06:00 PM
04/01/26
04/01/26
San Francisco 49ers
Seattle Seahawks
Prediction
Arizona Cardinals Last Match Played stats
Arizona Cardinals vs Green Bay Packers
Final Score :23 - 27
| (H) | Offense | (A) |
|---|---|---|
| 2 | Touchdowns | 3 |
| 3/3 | Field goals | 2/2 |
| 330 | Total yards | 262 |
| 1 | Turnovers | 0 |
| 2/4 | Red zone efficiency | 3/4 |
| 34:10 | Time of Possession | 25:50 |
| 23 | First downs | 19 |
| 4 | First downs by penalty | 5 |
| 7/14 (50%) | Third down efficiency | 3/10 (30%) |
| 1 | Punts | 3 |
| 42 | Average yards per punt | 58 |
| 4.7 | Average yards per play | 4.9 |
| (H) | Passing | (A) |
| 13 | First downs by passing | 10 |
| 236 | Net yards passing | 168 |
| 279 | Gross yards passing | 179 |
| 2 | Passing touchdowns | 1 |
| 0 | Interceptions thrown | 0 |
| 5.6 | Average passing yards per attempt | 5.6 |
| 6 | Red zone passing attempts | 4 |
| (H) | Rushing | (A) |
| 28 | Rushing attempts | 23 |
| 94 | Rushing yards | 94 |
| 3.4 | Average rushing yards per attempt | 4.1 |
| 5 | First downs by rushing | 5 |
| 3 | Red zone rushing attempts | 6 |
| (H) | Other | (A) |
| 6 | Penalties | 10 |
| 55 | Yards penalized | 94 |
| 1 | Fumbles | 2 |
| 1 | Fumbles lost | 0 |
San Francisco 49ers Last Match Played stats
Houston Texans vs San Francisco 49ers
Final Score :26 - 15
| (H) | Offense | (A) |
|---|---|---|
| 2 | Touchdowns | 2 |
| 4/4 | Field goals | 0/0 |
| 475 | Total yards | 223 |
| 1 | Turnovers | 1 |
| 1/5 | Red zone efficiency | 2/2 |
| 41:22 | Time of Possession | 18:38 |
| 23 | First downs | 12 |
| 0 | First downs by penalty | 1 |
| 9/16 (56%) | Third down efficiency | 3/9 (33%) |
| 2 | Punts | 5 |
| 48 | Average yards per punt | 47.6 |
| 6.3 | Average yards per play | 5.1 |
| (H) | Passing | (A) |
| 16 | First downs by passing | 10 |
| 318 | Net yards passing | 175 |
| 318 | Gross yards passing | 193 |
| 2 | Passing touchdowns | 2 |
| 1 | Interceptions thrown | 1 |
| 8.2 | Average passing yards per attempt | 5.1 |
| 3 | Red zone passing attempts | 4 |
| (H) | Rushing | (A) |
| 36 | Rushing attempts | 10 |
| 157 | Rushing yards | 48 |
| 4.4 | Average rushing yards per attempt | 4.8 |
| 6 | First downs by rushing | 2 |
| 3 | Red zone rushing attempts | 0 |
| (H) | Other | (A) |
| 8 | Penalties | 4 |
| 55 | Yards penalized | 30 |
| 0 | Fumbles | 1 |
| 0 | Fumbles lost | 0 |
NFL 25/26 Standings
| POS | TEAM | MP | W | L | D | PTS |
|---|---|---|---|---|---|---|
| 1 | 8 | 7 | 1 | 0 | 0.875 | |
| 2 | 7 | 5 | 1 | 1 | 0.786 | |
| 3 | 8 | 6 | 2 | 0 | 0.75 | |
| 4 | 8 | 6 | 2 | 0 | 0.75 | |
| 5 | 8 | 6 | 2 | 0 | 0.75 | |
| 6 | 8 | 6 | 2 | 0 | 0.75 | |
| 7 | 7 | 5 | 2 | 0 | 0.714 | |
| 8 | 7 | 5 | 2 | 0 | 0.714 | |
| 9 | 7 | 5 | 2 | 0 | 0.714 | |
| 10 | 7 | 5 | 2 | 0 | 0.714 | |
| 11 | 8 | 5 | 3 | 0 | 0.625 | |
| 12 | 8 | 5 | 3 | 0 | 0.625 | |
| 13 | 8 | 5 | 3 | 0 | 0.625 | |
| 14 | 7 | 4 | 3 | 0 | 0.571 | |
| 15 | 7 | 4 | 3 | 0 | 0.571 | |
| 16 | 7 | 4 | 3 | 0 | 0.571 | |
| 17 | 8 | 4 | 4 | 0 | 0.5 | |
| 18 | 8 | 3 | 4 | 1 | 0.438 | |
| 19 | 7 | 3 | 4 | 0 | 0.429 | |
| 20 | 7 | 3 | 4 | 0 | 0.429 | |
| 21 | 7 | 3 | 4 | 0 | 0.429 | |
| 22 | 8 | 3 | 5 | 0 | 0.375 | |
| 23 | 8 | 3 | 5 | 0 | 0.375 | |
| 24 | 8 | 3 | 5 | 0 | 0.375 | |
| 25 | 7 | 2 | 5 | 0 | 0.286 | |
| 26 | 7 | 2 | 5 | 0 | 0.286 | |
| 27 | 8 | 2 | 6 | 0 | 0.25 | |
| 28 | 8 | 2 | 6 | 0 | 0.25 | |
| 29 | 9 | 2 | 7 | 0 | 0.222 | |
| 30 | 8 | 1 | 7 | 0 | 0.125 | |
| 31 | 8 | 1 | 7 | 0 | 0.125 | |
| 32 | 8 | 1 | 7 | 0 | 0.125 |